From Tim Taylor:
Icon Restore gives you the ability to save the placement of your desktop icons and restore them to their saved placement any time they get moved. Simply place your icons wherever you want them on your desktop, right click My Computer (or any system icon) and left click on ‘save icon layout’ from the pop up menu. If your icons ever get moved because your computer entered safe mode or you changed the screen resolution, right click My Computer and left click on ‘restore icon layout’ from the pop up menu. It is the perfect solution for anyone that needs to change the screen resolution frequently.